Diet and women's health
Nutrition for breast cancer survivors
Maintaining a healthy diet is essential for breast cancer survivors. The survivors and their families are highly concerned about improving their health related behaviors and quality of life. However, little is known about the association between dietary factors and breast cancer prognosis, especially among Asian breast cancer survivors.
We started Korean breast cancer survivors’ recruitment from 2012 and are still in progress of inviting more participants. Collection of information on demographic factors, clinical and reproductive factors, and various lifestyle factors including intakes of foods and nutrients, and supplemental use is ongoing. Biological specimens are being collected from a subset of study participants.
The purposes of this study are 1) to evaluate the associations between dietary and anthropometric factors and breast cancer prognosis and 2) to provide important evidence to support the significance of promoting healthy diets for breast cancer survivors.
Filipino Women's Diet and Health Study (FiLWHEL)
The FiLWHEL study is a cohort study focusing on the health status of the Filipino women immigrants. The primary objectives of the FiLWHEL study are 1) to explore how lifestyle, environment, and genetic factors play a role in the health status of Filipino women; and 2) to promote healthy lifestyle and achieve the optimum level of well-being among Filipino immigrants.
The FiLWHEL study was launched on March 2014 and so far a total of 504 Filipino women, married to Korean men, are enrolled. The study collected biospecimen and a comprehensive information on various aspects of a participant's health-related life.
We are in progress of recruiting more Filipino women and presenting the results to provide a better and clearer understanding of the health status of this unique community that will play an integral part of the future of Korean society.
Korea Nurses' Health Study
The Korea Nurses' Health Study is a prospective cohort study of female nurses, with the goal of providing evaluations on associations of occupational, environmental, and lifestyle risk factors with health outcomes of Korean women.
Dietary assessment research
ICT-based dietary monitoring and assessment
Assessment of dietary intake is essential in estimating nutritional status and investigating the role of diet in the maintenance of health and the reduction of disease risk. Information and communication technology (ICT) has a potential to be utilized in dietary assessment as a monitoring tool of nutritional status in public health and epidemiology. We are conducting a randomized intervention trial to examine the effectiveness of ICT-based dietary assessment and monitoring.
Estimation of usual intake
Estimating daily consumption of foods and nutrients has been challenging due to the within-person variability in intake. There is a special interest in methods for estimating the habitual dietary intake distribution and its application to nutritional epidemiologic studies. We study methods for estimating the distribution of usual intake for a population and examining associations between usual dietary intakes and health outcomes.
Diet-Gene interaction research
Although recent studies found genetic factors related to chronic diseases such as obesity and cancer, it has been suggested that only a small proportion of heritability may be explained by the genetic variants. It has been hypothesized that gene-environment interaction may explain the missing heritability. For example, the association between dietary factors and disease outcomes may vary depending on specific genetic profile. We study whether particular diets accentuate risk of chronic diseases in a population with a certain genetic variation.
Diet and cancer
Diet serves an important role in the prevention of colorectal cancer. Colorectal adenoma is a precursor of colorectal cancer while screening prevents the development of colorectal cancer. Thus, the identification of risk factors of colorectal adenoma has great importance in public health implications in Korea, where colorectal cancer screening rate is high. Our research involves the investigation of dietary contributors to colorectal adenoma and cancer prevention.
Asia Cohort Consortium
The Asia Cohort Consortium is a collaborative research with a focus to understanding the associations between the relationships among genetics, environmental exposures, and the etiology of disease including cancer in more than 1 million Asian population. Our research has focused on the roles of dietary factors in cancer prevention and progression.